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Thesis Nootropics Review: Personalized, Nootropic Brain Support

Thesis Review

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About Thesis

You’ve likely felt that inner frustration throughout your workday when you feel as though your brain is moving through molasses—your processing speed of taking in information from your outside world, absorbing that, interpreting it within the crevices of your brain matter, and formulating a response (whether it be a movement, vocalized statement, or merely an inner thought), feels like a herculean task.

That strange sensation where you knew you forgot something, but all that your brain can recall is not what that something was but merely that it was something. It can be frustrating to say the least. While I have firm faith that, erase societal pressures and stressors, our fellow human brethren are some pretty intelligent souls, even I find myself questioning my intellectual couth some days.

So where is this intellectual, groggy deficit coming from? While it is not just a few identifiable causes, we live in a society filled with a glorification of severe routine, a practice of consuming and using synthetic chemicals, not inadvertently, but subtly, and the current social and economic stressors can be all too much—disrupting sleep, neuronal regeneration and thus, overall brain health.

But this is not all gloom and doom! Mother Nature has gifted us with some pretty potent brain protection: nootropics! Nootropics, called “smart drugs”, act on the brain to improve memory, cognitive function, and neuronal regeneration by improving the flow of blood, and thus essential nutrients, to the brain. (2) You may be thinking: this sounds incredibly expensive.

Not to worry because once brave soul decided to create an extensive line of nootropic blends to meet all your brain health qualms. Welcome, Thesis! With 86 winning formulations of nootropic blends to improve Creativity, Clarity, Motivation, Energy, and Logic, this review will focus on the effectiveness and composition of these purportedly stellar nootropic formulations.

Overview of Thesis

Founder and CEO, Dan Freed, found himself struggling in school as a child. He recalls rereading the same paragraph repeatedly, unable to understand the content despite functioning just fine in all other areas of life. Exhausted from the struggle and lack of support, he withdrew from school at the age of 16 and went to work in the restaurant industry.

But it clearly was not a learning deficiency as Dan eventually earned a Master’s Degree at Yale and went on to create the first-ever nootropic support with over 550,000 recommendations made by the scientific community and 127 tested ingredients to ensure maximum efficacy and bioavailability. Thesis offers five unique formulation to meet the common, daily need: Creativity, Clarity, Motivation, Energy, and Logic.

All of Thesis’s ingredients are noted to be purely sourced locally within the United States that bring you quality adaptogenic mushrooms, vitamins, minerals, and choline sources. Is Thesis the answer to a revived brain? Dan’s motto is, “Lazy doesn’t exist.” Let us find out if our brains need a total “reset” or merely some supportive, nootropic love.


Thesis believes in personalizing your experience to meet your needs in the most accurate form possible with their extensive questionnaire that queries your daily activities, energy levels, sleep cycle, caffeine intake, and more.

Quick and simple with effective results. Click here to begin your personalized journey to find your starter kit or, skip the quiz and build your own box here!

Thesis Products Review

Thesis offers 5 unique formulations to meet your daily mental support needs. Each crafted by a team set on ensuring maximum efficacy of each dosage of ingredient integrated, to give an idea of how prepared the Thesis team was in their first month of formulation, over 86% of each proposed formulation was approved—and praised—for its novel nootropic agencies.

With 96% purported customer satisfaction, perhaps Thesis’s reliance on the data speaks volumes to not only the integrity of products, but perhaps the communal effort in creating brain wellness. $119 each with retail price, or save $40 in the Thesis Subscribe & Save program, let’s take a dive into these pure and locally sourced, caffeine-free ingredients to find out more:

Thesis Creativity Review

Thesis’s Creativity blend is endorsed to increase that “spark” of inspiration, get your thought processes flowing into an easeful state of being, and improve your confidence in the process with four potent ingredients:

Alpha GPC (150mg): Alpha-glycerylphosphorylcholine (αGPC) is the precursor molecule to acetylcholine, an essential neurotransmitter that plays a role in cognition and mood by increasing serotonin in the cerebral portions of the brain and dopamine in the frontal lobe. (3)

Agmatine (250mg): A molecule that is thought to be produced by the gut microbiome, agmatine is an amine molecule that is believed to alleviate depressive-like symptoms and even support metabolic syndromes like diabetes and obesity; albeit the mechanism of such is unclear. (4)

Ginseng (200mg): A centuries-old remedy originating from East Asia, ginseng is known to be a preventative measure for neurodegeneration disorder, Alzheimer’s, as well as remediate depressive symptoms in numerous clinical studies. (5)

Ashwagandha (300mg): Ashwagandha, Withania somnifera, is an Ayurvedic wonder that is known for its natural adaptogenic (ability to handle stress in a methodical, sequential manner) properties, as well as its anxiolytic (anxiety-reducing) characteristics. Plus, in numerous clinical studies, there is statistically significant indication of ashwagandha’s antioxidant properties; helping to reduce free radicals that cause cellular damage and early signs of aging throughout numerous organ systems. (6,7)

Zembrin® (25mg): A proprietary blend containing selectium or also known as kanna, Mesembryanthemum tortuosum, Zembrin is known for its anti-anxiety properties that holds no sedative qualities but offers an elevate, peaceful state of being. (8)

Thesis Clarity Review

Thesis’s Clarity is endorsed to get you in—and improve—your flow state. With a heightened sense of focus and analytical processing, let’s see if the ingredients really live up to its name:

Alpha GPC (500mg): (see benefits in Creativity ingredient list above)

Lion’s Mane (500mg): Lion’s mane, Hericium erinaceus, has been studies in numerous scientific studies examining the effect of lion’s mane in reducing depressive episodes among patient with mild to severe depression by reducing an inflammation pathway that has been linked to worsening depression and possessing a chemical structure like dopamine and serotonin—the “happy” chemicals of the brain. Happy chemicals, clearer intention. (9)

Epicatechin (278mg): A potent flavanol found in apples, berries, cacao, and tea, within large scale studies, these molecules have been found to improve cerebral (brain) blood flow; improving flow of nutrients to neurons, aiding in repair and regeneration. (10)

7,8-DHF (30mg): 7,8 DHF, short for 7,8-dihydroxyflavone, is a humble, yet mighty molecule that is known to act on a vital pathway in the brain’s regenerative properties (acting similar to brain-derived neurotrophic factor). Why should we care and why with Thesis place this essential ingredient into their Clarity formulation? Studies suggest that because of 7,8 DHF’s ability to act on this pathway, we now have a way to consume on a daily basis a molecule that protects neurons from free radical damage and encourage neuronal growth. It seems the Thesis team has really placed the science and biology at the forefront of their formulations. (11)

Thesis Motivation Review

Take 30 minutes prior your daily tasks and settle into a routine of dedicated, goal-driven mindset to get you through any task you need to accomplish in the day ahead. How does Thesis make an impossible feat possible with its Motivation formulation? Let’s look:

Artichoke Extract: Although the scientific community is still seeking true influence of artichoke extract on brain protection, current studies have suggested that artichoke extract, rich in flavonoid, has an anticholinesterase blocking property. Why should we care? In certain neurodegenerative diseases (i.e., Alzheimer’s), blocking this anticholinesterase enzyme has been shown to improve the long-term outcomes of such diseases. With the added benefits of neuroprotection, we get why Thesis include artichoke extract in the Motivation ingredient line-up. (12)

Forskolin: A pure molecule extracted by the East Asian plant, Coleus forskohlii, known by the scientific community to increase cyclic adenosine monophosphate (cAMP) levels, this is vital for optimum cognition and, like the artichoke extract, acts as a neuroprotectant. (13)

L-Phenylalanine: One of the 26 amino acids, has been suggested to have a direct correlation between levels of l-phenylalanine and dopamine, the reward chemical. With dopamine, humans quite literally lose motivation for even the most primal of needs (i.e., eating, procreating, sleeping, etc.). Important to stay motivated? We think so, too. (12)

Vitamin B12: Also known as cobalamin, vitamin B12 is vital for cognitive function in both the central (brain and spinal cord) as well as peripheral nervous system; albeit the exact daily dose to provide this benefit is still debated amongst the medical community. (13)

Thesis Energy Review

It’s likely universally agreed that we could all use more of this currency (in addition to time!). But what makes Thesis’s Energy a true remedy for energy deficiency? Let’s peek:

Choline (300mg): According to Numerous clinical studies, choline, a nutrient present in eggs and liver, increases dopamine levels and assist in memory loss. Wonder if dopamine plays a role in energy? Absolutely it does! Our limbic reward system is directly ties to excitement and perceivable elevation of energy. (14)

Zynamite® (300mg): Known also as mangiferin (Mangifera indica), studies have suggested to have a synergistic effect during states of exercise by increasing the rates of oxygenation in the brain; supporting neurons with nutrient-dense electrolytes and glucose. Why did Thesis include this? More glucose to the brain means more sustained energy.  (15) 

TeaCrine® (100mg): Originating from the tree, Camellia kucha, TeaCrine has been known to support cognitive functioning as well as sustain energy throughout the day; especially when taken in conjunction with natural forms of caffeine (i.e., green tea extract). (16)

NAC (500mg): Although the mechanism as to whether NAC, N-acetyl cysteine, affects and promotes sustained energy levels throughout the day, researchers have noted potent antioxidant properties; suggesting there is some form of neurological protection as many neurodegenerative disorders are initiated by an inflammatory insult from free radicals. (17)

Sabroxy® (100mg): A study by Lopresti et al (2021) found that daily use of Oroxylum indicum extract (Sabroxy) had notable improvement in speed of processing thoughts when acquiring or approaching a new task in their subject groups. Important to sustain that energy by higher processing speeds? Absolutely. (18)

NALT (300mg): Known as N-acetyl tyrosine, NALT has been suggested to improve energy levels throughout the day as well as having evidence for improvement of dismantling longer term memory loss. (19)

Thesis Logic Review

So you have the energy, the motivation, the clarity, and creativity, but what is that all goof for if you quite literally have no logical sense of the actions you are performing? Thesis agrees. That is why they’ve included Logic in their mind wellness lineup. Although they have their handy quiz to help support you in your specific cognitive needs, we like to think we saved the one of the most important for last to review this powerful ingredient roster:

Ginkgo Biloba (160mg): Gingko biloba extract, coming from Ginkgo biloba, has a multitude of properties that all act in favor of your nervous system. Gingko biloba has been suggested to improve your innate levels of serotonin and dopamine, as well as improve long term cognition of hippocampal function and act as a free radial scavenger, protecting the prefrontal lobe where executive functioning takes place (i.e., the logical portion of your brain!). (20)

Theobromine (100mg): Extracted from the cacao tree, theobromine is believed to act on a series of pathways whereby improved working memory (your current memory that, for example, recalled the name of the company in which this article is written about). Important for logic? Without a doubt. Well done, Thesis team! (21)

Phosphatidylserine (400mg): Phosphatidylserine is known for its neuroprotective properties; supporting the myelin sheath (the protective layer around each neuron that improve its efficacy of neuronal transmission). (22)

DHA (200mg): Abbreviated DHA for docosahexaenoic acid, this is the most abundant omega-3 in the brain. This molecule integrates into the cellular integrity of brain cells to ensure structural integrity. Think of this as the “grease” that ensures the brain is functioning with optimum logic. (23)

TAU (30mg): Tau is a protein found within the brain that, when it becomes misfolded during its production from DNA into protein, it can become a conglomerate of protein mass that causes the ever-so-known neurodegenerative disease, Alzheimer’s. Logic is severely limited in these cases that is why Thesis utilizes a tau-target remedy as a proactive measure; keeping your logic in-tact for decades to come? Perhaps so. (24)

Synapsa® (320mg): Although unable to find from scientific articles, Thesis endorses on their site that Synpasa® comes from the extract of Bacopa Monnieri that is suggested “to improve cognitive function as well as overall neurological health.”(25)

Thesis Reviews – Customer Testimonies

What are customers saying about the efficacy of Thesis’s lineup of memory-enhancing, brain-protecting, logic-boosting formulations?

George L., a verified customer shares:

“I absolutely love this stuff, seriously. I’ve tried just about every nootropic in addition to making formulas for myself, but nothing comes close to Thesis. I’m actually shocked at how well it works. I work anywhere from 10-14 hours seven days a week and I can feel myself and being more motivated, even after 14 hours, I’ll be a customer for life and I recommend your products to my people.”

It’s always great to see a former skeptic take a complete 180-degree turn and find so much benefit in a product that they  intend to keep it as a daily regiment for life. Quality speaks for itself.

Debbie M writes her experience with Thesis Creativity:

“I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work. Thank you for making such an amazing product.”

A happy mom is a happy household. Plus, to hear your fellow humanity share that they are “thinking outside of the box” in a world that is seemingly placing everyone with a “label” what an incredible breakthrough! The power of nootropics and adaptogens at its finest!

Kyle B. shares a heartfelt response on his experience with Thesis products and the team:

“You guys have been a lifesaver for me. I’m not sure how I could have done this past year without some help and you really were there for me. Great experiences and awesome customer service!”

Amazing, integrity inside and out—well done, Thesis.

Most recently, Elliott S. shares his initial skepticism with taking Thesis for the first time:

“I’m going to be honest with you, I was skeptical but I started a new job so I thought maybe it could help. Within a half hour of the first time taking it I saw immediate results. I’m more alert and focused than I’ve been in years. I’m so happy I found Thesis as it has been life changing for me so far.”

Skepticism is good—it means you think before you jump on the latest and greatest health fad. Amazingly, it seems Thesis has erased all wavering on efficacy for Elliott. Thesis products seemingly prove time and again.

Frequently Asked Questions

Subscribe & Refer A Friend Program

Join Thesis’s Subscribe Program to receive $40 off every order you spend. Cancel or modify without any additional fee. Get your nootropics for a fraction of the cost!

For every friend you refer to Thesis, your friend will receive $25 off their next order and a $25 credit will be applied to your account upon your next purchase! Share the nootropic goodness!

Community Mission

The team at Thesis believes in supporting not just their customers, but their community in the form of sending a part of their proceeds to The Covenant House, a homeless shelter for runaway and at-risk youth. CEO, Dan Freed, knows firsthand what it is like to be at the mercy of an unforgiving system. What better way than to give back? Much respect, team Thesis.

Where Can I Find Thesis?  

Thesis can be found on their main site at Thesis and on their Instagram page, @takethesis.

Final Takeaway

Functional mushrooms to meet your daily cognitive needs? Thesis has created an extensive, yet poignant, lineup of Creativity, Energy, Motivation, Logic, and Clarity. With potent nootropics like lion’s mane, choline, alpha GPC, and ayurvedic powerhouses including ashwagandha and gingko biloba, Thesis has seemingly integrated a handful of pure ingredients into each formulation that is cGMP certified and locally sourced within the United States.

With community outreach to help serve organizations that service homeless children, Thesis was based on a mission beyond their consumer wellness. CEO, Dan Freed, wanted humanity to know that they are not alone. The mental fogginess, the inability to concentrate for longer sets of time, inability to foster an ounce of creativity, Dan knew this wasn’t a human deficiency but  a nutrient deficiency.

Tired of wondering if your mental strain could be remedied by daily consumption of a personalized nootropic lineup? Thesis might just offer the personalized support you’ve been seeking.

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Grace Morse

Grace Morse is a passionate advocate of holistic healing. Over the past two decades, in conjunction with her graduate-level medical knowledge, Grace has gathered ample knowledge of integrating omegas to promote neuroplasticity, healing depression via amino acids, replacing melatonin and sleep pills with L-theanine and bringing her gut health back to homeostasis by avoiding high-inflammatory foods. Grace practices hot yoga, meditation, and outdoor activities like paddle boarding. Inspired by Ayurveda, she seeks to deepen her understanding of holistic practices and encourages others to embrace mind-body wellness for overall well-being.
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